2018

184.Wang, H.; Song, Z.; Lao, Y.; Xu, X.; Gong, J.; Cheng, D.; Chakraborty, S.; Park, J.S.; Li, M.; Huang, D.; Yin, L.; Cheng, J.; Leong, K.W. “Nonviral Gene Editing via CRISPR/Cas9 Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide “, PNAS, (NIH-HL109442; NIH-AI096305; NIH-GM110494; NIH-UH3 TR000505) [PDF] [SI] [Link]

183. Song, Z.; Fu, H.; Wang, R.; Pacheco, L.A.; Wang, X.; Lin, Y.; Cheng, J. “Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications”, Chem. Soc. Rev., 2018, 47, 7401-7425. (NSF-CHE-1709820; NSF-CHE-1308485 ) [PDF] [Link]

182. Lv, S.; Wu, Y.; Cai, K.; He, H.; Li, Y.; Lan, M.; Chen, x.; Cheng, J.; Yin, L. “High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions”, J. Am. Chem. Soc., 2018, 140, 1235–1238. [PDF][SI][Link]

181. Zhang, Y.; Cai, K.; Li, C.;  Guo, Q.; Chen, Q.; He, X.; Liu, L.; Zhang, Y.; Lu, Y.; Chen, X.; Sun, T.; Huang, Y.; Cheng, J.; Jiang, C. “Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy”, Nano Lett.201818, 1908–1915. (NSF-Grant 81425023; NSF-DMR-1309525 ; NIH-R01 1R01CA207584 and R21 CA198684)  [PDF] [SI] [Link]

180. He, H.; Chen, Y.; Li, Y.; Song, Z.; Zhong, Y.; Zhu, R.; Cheng, J.; Yin, L. “Effective and Selective Anti-Cancer Protein Delivery via All-Function-in-One Nanocarriers Coupled with Visible Light-Responsive, Reversible Protein Engineering”, Adv. Funct. Mater., 2018, DOI: 10.1002/adfm.201706710. [PDF][SI][Link]

179. He, X.; Zhang, J.; Li, C.; Zhang, Y.; Lu, Y.; Zhang, Y.; Liu, L.; Ruan, C.; Chen, Q.; Chen, X.; Guo, X.; Sun, T.; Cheng, J.; Jiang, C. “Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy”, Theranostics, 2018, 8, 4884

178. He, X.; Cai, K.; Zhang, Y.; Lu, Y.; Guo, Q.; Zhang, Y.; Liu, L.; Ruan, C.; Chen, Q.; Chen, X.; Li, C.; Sun, T.; Cheng, J.; Jiang, C. “Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy”, ACS applied materials & interfaces, 2018, 10, 39455-39467

177. Ying, H.;  Yang, Y.; Cai, K.; Cheng, J. “Hindered Urea Bond: A Bilaterally Responsive Chemistry to Hydrogen Peroxide”, Eur. J. Org. Chem., 2019, 728-731. (NSF CHE 17-09820; American ChemicalSociety Petroleum Research Fund (58671-ND7)). [PDF] [SI[Link]

176. Liu, L.; Wang, R.; Wang, C.; Wang, J.;  Chen, L.; Cheng, J. “Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy”, Biomater. Sci., 2018,6, 997-1001. [PDF] [SI] [Link]

175. Liu, Y.; Song, Z.; Zheng, N.; Nagasaka, K.; Yin, L.; Cheng, J. “Systemic siRNA delivery to tumors by cell-penetrating α-helical polypeptide-based metastable nanoparticles”, Nanoscale, 2018, 10, 15339–15349. (NSF-CHE 1709820; NIH-1R01CA207584) [PDF] [SI] [Link]

174. Wan, J.; Sun, L.; Wu, P.; Wang, F.; Guo, J.; Cheng, J.; Wang, C. “Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy”, Biomaterials Science, 2018, 6, 997-1001

173. Cai, K.; Ying, H.; Cheng, J. “Dynamic Ureas with Fast and pH-independent Hydrolytic Kinetics”, Chem. Eur. J., 2018, 24, 7345 –7348. (NSF-CHE15‐08710) [PDF] [SI] [Link]

172. Wang, R.; Cai, K.; Wang, H.; Yin, C.;  Cheng, J. “A caged metabolic precursor for DT-diaphorase responsive cell labeling”, Chem.Comm., 2018, 54, 4878–4881. (NIH-R21 1R21CA198684; NIH-1R01CA207584) [PDF] [Link]

171. Wan, J.; Sun, L.; Wu, P.; Wang, F.; Guo, J.; Cheng, J.; Wang, C. “Synthesis of indocyanine green functionalized comblike poly (aspartic acid) derivatives for enhanced cancer cell ablation by targeting the endoplasmic reticulum”, Polymer Chemistry, 2018, 9, 1206-1215. [PDF] [SI] [Link]

170. Yin, Q.; Tang, L.; Cai, K.; Yang, X.; Yin, L.; Zhang, Y.; Dobrucki, L.W.; Helferich, W.G.; Fan, T.M.; Cheng, J. “Albumin as a “Trojan Horse” for Polymeric Nanoconjugates Transendothelial Transport across Tumor Vasculatures for Improved Cancer Targeting”, Biomater. Sci., 2018, 6, 1189–1200. (NIH-1R01CA207584 ; NIH-1R21CA198684) [PDF] [SI] [Link]