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63. Gabrielson, N.P.; Lu, H.; Yin, L.; Li, D.; Wang, F.; Cheng, J. “Reactive and Bioactive Cationic a-Helical Polypeptide Template for Non-Viral Gene Delivery”, Angew. Chem. Int. Ed.2012, 51, 1143-1147. (NSF-CHE0809420; NIH-1R21EB009486-01; NIH-1DP2OD007246-01; NIH-1R21CA152627; PMC3555134; NIH-MS400098) [PDF] [SI] [Link]

62. Tong, R.; Cheng, J. “Zinc complex mediated regioselective O-acylation of therapeutic agents”, Chemical Science, 2012, 3, 2234-2239. [PDF] [SI[Link]

61. Gabrielson, N. P.; Lu, H.; Yin, L.; Kim, K.H.; Cheng, J. “A Cell-Penetrating Helical Polymer for siRNA Delivery to Mammalian Cells”, Molecular Therapy, 2012, 20, 1599-1609. (NSF-CHE0809420; NIH-1R21EB013379-01; NIH-1DP2OD007246-01; PMC3412491) [PDF] [Link]

60. Tong, R.; Gabrielson, N.P.; Fan, T.M.; Cheng, J. “Polymeric Nanomedicine Based on Poly(lactide) and Poly(lactic-co-glycolide)”, Current Opinion in Solid State & Materials Science, 2012, 16, 323-332. (PMC3728009; NIH-MS439167) [PDF] [Link]

59. Zhang, Z.; Yin, L.; Xu, Y.; Ren, J.; Cheng, J. “Facile Functionalization of Polyesters through Thiol-yne Chemistry for the Design of Degradable, Cell‒Penetrating and Gene Delivery Dual‒Functional Agents”, Biomacromolecules, 2012, 13, 3456-3462. (NIH-1R21EB013379-01; NIH-1DP2OD007246-01; NSF-CHE1153122; PMC3606898; NIH-MS417829) [PDF] [SI[Link]

58. Tang, H.; Yin, L.; Lu, H.; Cheng, J. “Water-Soluble Poly(L-serine)s with Elongated and Charged Side-Chains: Synthesis, Conformations and Cell-Penetrating Properties”, Biomacromolecules, 2012, 13, 2609-2615. (NIH-1R21EB013379-01; NIH-1DP2OD007246-01; PMC3555145; NIH-MS401030) [PDF] [SI[Link]

57. Cely, I.; Yiv, S.;Yin, Q.; Shahidzadeh, A.; Tang, L.; Cheng, J.; Uckun, F.M. “Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles”, J. Anal. Oncol., 2012, 1, 1-9. (NIH-1DP2OD007246-01; PMC3668349; NIH-MS406536) [PDF[Link]

56. Li, L.; Yin, Q.; Cheng, J.; Lu, Y. “Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells”, Adv. Healthcare Mater., 2012, 1, 567-572. (NIH-1DP2OD007246-01; NIH-1R21CA152627) [PDF] [SI[Link]

55. Tang, L.; Azzi, J.; Kwon, M.; Mounayar, M.; Tong, R.; Yin, Q.; Moore, R.; Skartsis, N.; Fan, T.M.; Abdi, R.; Cheng, J. “Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A”, Journal of Transplantation, 2012896141, 1-9. (NIH-1DP2OD007246-01; NIH-1R21CA152627; PMC3321582) [PDF] [Link]

54. Tang, L.; Fan, T.M.; Borst, L.B.; Cheng, J. “Synthesis and Biological Response of Size-Specific, Monodisperse Drug-Silica Nanoconjugates”, ACS Nano., 2012, 6, 3954-3966. (NIH-1DP2OD007246-01; NIH-1R21CA152627; PMC3555148; NIH-MS372943) [PDF] [SI][Link]

53. Lu, Y.; Yin, L.; Zhang, Y.; Zhang, Z.; Xu, Y.; Tong, R.; Cheng, J. “Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-L-serine Carboxyanhydrides”, ACS Macro Letters, 2012, 1, 441-444. (DMR 07-48834, 1DP2OD007246-01, 1R21EB013379-01; PMC3555137, NIHMS363858) [PDF] [SI] [Link]

52. Tong, R.; Cheng, J. “Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates”, Macromolecules, 2012, 45, 2225-2232. (NSF-DMR07-48834; NIH-1DP2OD007246-01; PMC3555138; NIH-MS359696) [PDF][SI] [Link]

51. Chen, K.; Tang, L.; Garcia, M.A.; Wang, H.; Lu, H.; Lin, W.; Hou, S.; Yin, Q.; Shen, C.K.F.; Cheng, J.; Tseng, H.R. “The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles”, Biomaterials, 2012, 33, 1162-1169. (NIH-1R21CA152627; PMC3786683; NIH-MS333953) [PDF] [SI] [Link]