Google Scholar Citations


    157. Wang, H.; Wang, R.; Cai, K.; He, H.; Liu, Y.; Yen, J.; Wang, Z.; Xu, M.; Sun, Y.; Zhou, X.; Yin, Q.; Tang, L.; Dobrucki, I.T.; Dobrucki, L.W.; Chaney, E.J.; Boppart, S.A.; Fan, T.M.; Lezmi, S.; Chen, X.; Yin, L.; Cheng, J. "Selective In Vivo Metabolic Cell Labeling Mediated Cancer Targeting", Nature Chemical Biology, Published online 13 February 2017. (1DP2OD007246, NSF-DMR 1309525) [Link] [Highlighted by Chemical and Engineering News]

    156. Baumgartner, R.; Fu, H.; Song, Z.; Lin, Y.; Cheng, J. "Cooperative polymerization of α-helices induced by macromolecular architecture", Nature Chemistry, Published online 06 February 2017. (CHE-1308485, CHE-1508710) [Link]

    155. Cai, K.; Wang, A.Z.; Yin, L.; Cheng, J. Bio-Nano Interface: The Impact of Biological Environment on Nanomaterials and Their Delivery Properties", J. Controlled Release, Published online 3 January 2017. (NSF-DMR 1309525, NSF-CHE 1508710) [Link].

    154. Lv, S.; Wua, Y.; Dang, J.; Tang, Z.; Song, Z.; Ma, S.; Wang, X.; Chen, X.; Cheng, J.; Yin, L. "Investigation on the controlled synthesis and post-modification of poly-[(N-2-hydroxyethyl)-aspartamide]-based polymers", Polymer Chemistry, Published online 07 February 2017. [Link]

    153. Zheng, N.; Song, S.; Liu, Y.; Yin, L.; Cheng, J. "Gene delivery into isolated Arabidopsis thaliana protoplasts and intact leaves using cationic, α-helical polypeptide", Frontiers of Chemical Science and Engineering, Published online 13 January 2017. [Link]


    152. Yin, Q.; Tang, L.; Cai, K.; Tong, R.; Sternberg, R.; Yang, X.; Dobrucki, L.W.; Borst, L.B.; Kamstock, D.; Song, Z.; Helferich, W.G.; Cheng, J.; Fan, T.M. "Pamidronate Functionalized Nanoconjugates for Targeted Therapy of Focal Skeletal Malignant Osteolysis", PNAS, 2016, 113, E4601-4609. (1DP2OD007246, NSF-DMR 1309525; PMC4987772) [PDF] [SI] [Link]

    151. Wang, R.; Zhang, J.; Yin, Q.; Xu, Y.; Cheng, J.; Tong, R. "Controlled Ring-Opening Polymerization of O-Carboxyanhydrides Using β-Diiminate Zinc Catalyst", Angew. Chem. Int. Ed.,  2016, 55, 13010-13014. (NSF-CHE-1308485) [PDF] [SI] [Link]

    150. Wang, H.; Gauthier, M.; Kelly, J. R.; Miller, R.J.; Xu, M.; O'Brien, W.D.; Cheng, J. "Targeted Ultrasound Assisted Cancer-Selective Chemical Labeling and Subsequent Cancer Imaging via Click Chemistry", Angew. Chem. Int. Ed., 2016, 55, 5452-5456. (1DP2OD007246, NSF-DMR 1309525; PMC4918225) [PDF] [SI] [Link]

    149. Tian, J.; Rodgers, Z.; Min, Y.; Wan, X.; Qiu, H.; Mi, Y.; Tian, X.; Wagner, K.T.; Caster, J.M.; Qi, Y.; Roche, K.; Zhang, T.; Cheng, J.; Wang, A.Z. "Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer", Nanomedicine: Nanotechnology, Biology, and Medicine, Published online. [Link]

    148. Wang, J.; Yuan, L.; Wang, Z.; Rahman, Md A.; Huang, Y.; Zhu, T.; Wang, R.; Cheng, J.; Wang, C.; Chu, F.; Tang, C. "Photoinduced Metal-Free Atom Transfer Radical Polymerization of Biomass Based Monomers",  Macromolecules, 2016, 49, 7709-7717. [PDF] [SI] [Link]

    147. Zheng, N.; Liu, Y.; Cheng, J. Gene Delivery Method Using Photo-Responsive Poly(b-Amino Ester), Non-Viral Gene Delivery Vectors, edited by Candiani, G., Humana Press, 2016, 259-267.

    146. Yin, L.; Zheng, N., Cheng, J. Highly Efficient siRNA Delivery Mediated by Cationic Helical Polypeptides and Polypeptide-Based Nanosystems, siRNA Delivery Methods,  edited by Shum, K. and Rossi, J., Humana Press, 2016, 37-47.

    145. Baumgartner, R.; Ryba, K.; Song,Z.; Wang, R.; Harris, K.; Katzd, J.S.; Cheng, J."A delayed curing ROMP based thermosetting resin", Polymer Chemistry, 2016, 7, 5093-5098. (Dow Chemical Company) [PDF] [SI] [Link]

    144. Xing, H.; Xu, W.; Hwang, K.; Wu, P.; Yin, Q.; Li, Z.; Cheng, J.; Lu, Y. "The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin", CHEMBIOCHEM, 2016, 17, 1111-1117. [PDF] [Link]

    143. Wang H.; Tang L.; Liu Y.; Dobrucki I.T.; Dobrucki L.W.; Yin L.; Cheng J. "In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates", Theranostics 2016, 6, 1467-1476. (1DP2OD007246-01, NSF-DMR 1309525; PMC4924513)[PDF] [Link]

    142. Song, Z.; Huang, Y.; Prasad, V.; Baumgartner, R.; Zhang, S.; Harris, K.; Katz, J.S.; Cheng, J. "Preparation of Surfactant-Resistant Polymersomes with Ultrathick Membranes through RAFT Dispersion Polymerization", ACS Applied Materials & Interfaces, 2016, 8, 17033-17037. (Dow Chemical Company) [PDF] [SI] [Link]

    141. Bai, Y.; Nguyen, L.T.; Song, Z.; Peng, S.; Lee, J.; Zheng, N.; Kapoor, I.; Lauren D. Hagler, L.; Cai, K.; Cheng, J.; Chan, H.Y.; Zimmerman, S.C. "Integrating Display and Delivery Functionality with a Cell Penetrating Peptide Mimic as a Scaffold for Intracellular Multivalent Multi-targeting", J. Am. Chem. Soc., 2016, 138, 9498-9507.[PDF] [Link]

    140. Zhang, Y.; Ying, H. (co-first author); Hart, K.R.; Wu, Y.; Hsu, A.J.; Coppola, A.M.; Kim, T.A.; Yang, K.; Sottos, N.R.; White, S.R.; Cheng, J. "Malleable and Recyclable Poly(urea-urethane) Thermoset Bearing Hindered Urea Bonds", Advanced Materials, 2016, 28, 7646-7651. (CHE 1508710) [PDF] [SI] [Link]

    139. Azzi, J.; Yin, Q.; Uehara, M.; Ohori, S.; Tang, L.; Cai, K; Ichimura, T.; McGrath, M.; Maarouf, M.; Kefaloyianni, E.; Loughhead, S.; Petr, J.; Sun, Q.; Kwon, M.; Tullius, M.; Andrian, U.; Cheng, J.; Abdi, R. "Targeted delivery of immunomodulators to lymph nodes", Cell Reports, 2016, 15, 1202-1213. (1DP2OD007246-01, NSF-CHE 1308485; PMC4973867) [PDF] [SI] [Link]

    138. Ying, H.; Cheng, J. One-step Construction of Aminosquaraine Backbone, Dyes and pigments, 2016, 131, 264-267. (CHE 1508710) [PDF] [Link]

    137. He, H.; Zheng, N.; Song, Z.; Kim, K.H.; Yao, C.; Zhang, R.; Zhang, C.; Huang, Y.; Uckun, F.M.; Cheng, J.; Zhang, Y.; Yin, L. "Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles", ACS NANO, 2016, 10, 1859-1870. (CHE 1508710) [PDF] [SI] [Link]

    136. Li, Y.; Bai, Y.; Zheng, N.; Liu, Y.; Vincil, G.A.; Pedretti, B.J.; Cheng, J.; Zimmerman, S. "Crosslinked Dendronized Polyols as a General Approach to Brighter and More Stable Fluorophores", Chemical Communications, 2016, 52, 3781-3784. [PDF] [SI] [Link]

    135. Yen, J. ; Ying, H.; Wang, H.; Yin, L; Uckun, F.; Cheng, J. "CD44 Mediated Non-Viral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic Acid Coated Nanoparticles",  ACS Biomaterials Science & Engineering, 2016, 2, 326-335. (1DP2OD007246, 1R21EB013379, CHE-1153122) [PDF] [Link] [COVER]

    134. Kang, S.; Murphy, R.; Hwang, S.; Lee, S.; Harburg, D.; Krueger, N.; Shin, J.; Gamble, P.; Cheng,H.; Yu, S.; Liu, Z.; McCall, J.; Stephen, M.; Ying, H.; Kim, J.; Park, G.; Webb, R.; Lee, C.; Chung, S.; Wie, D.; Gujar, A.; Cheng, J.; Huang, Y.; Lee, S.; Braun, P.; Ray, W.; Rogers, J.A. " Bioresorbable Silicon Electronic Sensors for the Brain", Nature, 530, 71-76. [PDF] [Link]




    133. Xiong, M.; Lee, M.W.; Mansbach, R.A.; Song, Z.; Bao, Y; Jr. Peek, R. M.;  Yao, C; Chen, Lin-Feng; Ferguson, A.L.;  Wong, G.C.L.; Cheng, J. "Helical Antimicrobial Polypeptides with Radial Amphiphilicity", PNAS, 2015, 112, 13155-13160. (1DP2OD007246, 1R21EB013379, R21AI117080, CHE-1153122; PMC4629321) [PDF] [SI] [Link]

    132. Cai, K.; He, X.; Song, Z.; Yin, Q.; Zhang, Y.; Uckun, F.M.; Jiang, C.; Cheng, J. "Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency", J. Am. Chem. Soc., 2015, 1373458-3461. (1DP2OD007246-01, 1R21CA152627, DMR 07-48834, NSF-DMR 1309525) [PDF] [SI] [Link]

    131. Tang, L.; Yin, Q.; Xu, Y.; Zhou, Q.; Cai, K.; Yen, J.; Dobrucki, L.W.; Cheng, J. "Bioorthogonal Oxime Ligation Mediated in Vivo Cancer Targeting", Chemical Science, 2015, 6, 2182-2186. (1DP2OD007246-01, DMR 07-48834; PMC4486360, NIHMS661301) [PDF] [Link]

    130. Wu, X.; He, C.; Wu, Y.; Chen, X.; Cheng, J. "Nanogel-Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo-Protein Combination Therapy", Advanced Functional Materials, 2015, 25, 6744-6755. [PDF] [SI] [Link]

    129.  Priftis, D.; Leon, L.; Song, Z.; Perry, S.L.; Margossian, K.O.; Tropnikova, A.; Cheng, J.; Tirrell M. "Self-Assembly of Alpha-Helical Polypeptides Driven by Complex Coacervation", Angew. Chem. Int. Ed., 2015, 54, 11128-11132. (NSF-CHE1153122) [PDF] [SI] [Link]

    128. Gauthier, M.; Yin, Q.; Cheng, J.; O'Brien W.D. "Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles", J Ultrasound Med, 2015, 34, 1363-1372. (1DP2OD007246-01; PMC4536807,NIHMS712338) [PDF] [Link]

    127. Lee, J.S.; Deng, X.; Han, P.; Cheng, J. "Dual Stimuli-Responsive Poly(beta-amino ester) Nanoparticles for On-Demand Burst Release", Macromolecular Bioscience, 2015, 15, 1314-1322. (1DP2OD007246-01) [PDF] [SI] [Link]

    126. Yin, Q.; Yin, L.; Wang, H.; Cheng, J. "Synthesis and biomedical applications of functional poly(alpha-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides", Accounts of Chemical Research, 2015, 48, 1777-1787. (1DP2OD007246-01) [PDF] [Link]

    125. Uckun, F.M.; Mitchell, L.G.; Qazi, S.; Myers, D.E.; Ma, H.; Zheng, N.; Song, Z.; Liu, Y.; Cheng, J. "Development of Polypeptide-Based Nanoparticles for Non-Viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL", EBioMedicine, 2015, 2, 649-659. (1DP2OD007246-01, NSF-CHE 1308485; PMC4534679) [PDF] [Link]

    124. Song, Z.; Kim, H.; Ba, X.; Baumgartner, R.; Lee, J.; Tang, H.; Leal, C.; Cheng, J. "Polypeptide Vesicles with Densely Packed Multilayer Membranes", Soft Matter, 2015, 11, 4091-4098. (Dow Chemical Company, NSF-CHE 1308485)  [PDF] [SI] [Link]

    123. Uckun, F.M.; Qazi, S.; Cheng, J.; Myers, D.E. "Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-precursor Leukemia and Yield Superior Survival Outcomes in Mice EBioMedicine",  EBioMedicine, 2015, 2, 554-562. (1DP2OD007246-01; PMC4535154) [PDF] [Link]

    122. Torabi, S.F.; Wu, P.; McGhee, C.E.; Chen, L.; Hwang, K.; Zheng, N.; Cheng, J.; Lu, Y. "In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing", PNAS, 2015, 112, 5903-5908. (PMC4434688) [PDF] [Link]

    121. Tang, L.; Tong, R.; Coyle, V.J.; Yin, Q.; Pondenis, H.; Borst, L.B.; Cheng, J.; Fan, T.M. "Targeting Tumor Vasculature with Aptamer Functionalized Doxorubicin-Polylactide Nanoconjugates for Enhanced Cancer Therapy", ACS Nano, 2015, 9, 5072-5081. [PDF] [SI] [Link].

    120. Uckun, F.M.; Qazi, S.; Cheng, J. "Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles", Future Oncology, 2015, 11, 1149-1152. (1DP2OD007246-01) [PDF] [Link]

    119. Baumgartner, R.; Song, Z.; Zhang, Y.; Cheng, J. "Functional Polyesters Derived from Alternating Copolymerization of Norbornene Anhydride and Epoxides", Polymer Chemistry, 2015, 6, 3586-3590. (Dow Chemical Compay) [PDF] [SI] [Link]

    118. Zhang, Y.; Yin, Q.; Yen, J.; Li, J.; Ying, H.; Wang, H.; Hua, Y.; Chaney, E.; Boppart, S.; Cheng, J. "Non-Invasive, Real-Time Reporting Drug Release In Vitro and In Vivo", Chemical Communications, 2015, 51, 6948-6951. (1DP2OD007246-01; PMC4486253, NIHMS674723) [PDF] [SI] [Link]

    117. Andrade, B.; Song, Z.; Li, J.; Zimmerman, S.; Cheng, J.; Moore, J.S.; Harris, K.; Katz, J. "New Frontiers for Encapsulation in the Chemical Industry",  ACS Applied Materials & Interfaces, 2015, 7, 6359-6368. (Dow Chemical Company) [PDF] [Link]

    116. Wang, H.C.; Zhang, Y.; Possanza, C.; Zimmerman, S.; Cheng, J.; Moore, J.; Harris, K.; Katz, J. " Trigger Chemistries for Better Industrial Formulations", ACS Applied Materials & Interfaces, 2015, 76369-6382. (Dow Chemical Company) [PDF] [Link]

    115. Wang, H.; Xu, M.; Xiong, M.H.; Cheng, J. " Reduction-Responsive Dithiomaleimide-Based Nanomedicine with High Drug Loading and FRET-Indicated Drug Release ", Chemical Communications2015, 51, 4807-4810. (NSF-DMR 1309525, 1DP2OD007246-01; NIHMS666739) [PDF] [SI] [Link]

    114. Zheng, N.; Song, Z.; Liu, Y.; Zhang, R.; Zhang, R.; Yao, C.; Uckun, F.M.; Yin, L.; Cheng, J. "Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery", J. Controlled Release2015, 205, 231-239. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01) [PDF] [Link]

    113. Uckun, F.M.; Ma, H.; Cheng, J.; Myers, D.E.; Qazi, S. "CD22deltaE12 as a molecular target for RNAi therapy", British Journal of Haematology,  2015, 169, 401-414. (1DP2OD007246-01) [PDF] [SI] [Link]

    112. Cai, K.; Yen, J.; Yin, Q.; Liu, Y.; Song, Z.; Lezmi, S.; Zhang, Y.; Yang, X.; Helferich, W.G.; Cheng, J. "Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics", Biomaterials Science2015, 3, 1061-1065. (DMR 07-48834, NSF-DMR 1309525, 1DP2OD007246-01, 1R21CA152627; NIHMS664361) [PDF] [SI] [Link]

    111. Yin, L.; Chen, Y.; Zhang, Z.; Yin, Q.; Zheng, N.; Cheng, J. "Biodegradable Micelles Capable of Mannose-Mediated Targeted Drug Delivery to Cancer Cells", Macromolecular Rapid Communications, 2015, 36, 483-489. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS683282) [PDF] [SI] [Link]

    110. Ma, L.; Baumgartner, R.; Zhang, Y.; Song, Z.; Cai, K.; Cheng, J. "UV-Responsive Degradable Polymers Derived from 1-(4-Aminophenyl) ethane-1, 2-diol", Journal of Polymer Science, Part A, 2015, 53, 1161-1168. (Dow Chemical Company) [PDF] [SI] [Link] [Cover]

    109. Zhang, R.; Song, Z.; Yin, L.; Lu, H.; Gabrielson, N.P.; Cheng, J. "Ionic α-Helical Polypeptides towards Non-Viral Gene Delivery" WIREs Nanomedicine & Nanobiotechnolog, 2015, 7, 98-110. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS631933) [PDF] [Link]




    108. Qu, Q.; Dong, L.; Louis, K.R.; Li, X.; Yang, H.; Sun, Q.; Crandall, S.R.; Tsang, S.; Zhou, J.; Cox, C.L.; Cheng, J.; Wang, F. "High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1", Nature Communications, 2014, 5, 3449. [PDF] [Link]


    107. Ying, H.; Zhang, Y.; Cheng, J. "Dynamic urea bond for the design of reversible and self-healing polymers", Nature Communications, 2014, 5, 3218. (NSF-CHE 1153122, 1DP2OD007246-01; NIHMS554614) [PDF][Link]


    106.  Tang, L.; Yang, X.; Yin, Q.; Cai, K.; Wang, H.; Chaudhury, I.; Yao, C.;Zhou, Q.; Kwon, M.; Hartman, J.A.; Dobrucki, I.T.; Dobrucki, L.W.; Borst, L.B.; Lezmi, S.; Helferich, W.G.; Ferguson, A.L.; Fan, T.M.; Cheng, J. "Investigating the optimal size of anticancer nanomedicine", PNAS, 2014, 111, 15344-15349. (1DP2OD007246-01, 1R21CA152627; PMC4217425) [PDF[Link]


    105. Ying, H.; Cheng, J. "Hydrolysable Polyureas Bearing Hindered Urea Bonds", J. Am. Chem. Soc., 2014, 136, 16974-16977. (NSF-CHE 1153122, 1DP2OD007246-01) [PDF] [Link]


    104. Uckun, F.M.; Qazi, S.; Ma, H.; Yin, L.; Cheng, J. "A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies", EBioMedicine, 2014, 1, 141-155.  (1DP2OD007246-01; PMC4292938, NIHMS644169) [PDF] [Link]


    103. Yin, L.; Huang, X.; Xu, H.; Zhang, Y.; Lam, J.; Cheng, J.; Rogers, JA. "Materials, Designs, and Operational Characteristics for Fully Biodegradable Primary Batteries", Advanced Materials, 2014, 26, 3879-3884. [PDF] [Link]


    102. Yen, J.; Yin, L.; Cheng, J. "Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure",  Journal of Materials Chemistry B,  2014, 2, 8098-8105. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE 1153122; NIHMS632808) [PDF] [Link]


    101. Zheng, C.; Niu, L.; Pan, W.; Zhou, J.; Lv, H.; Cheng, J.; Liang, D.; "Long-term kinetics of DNA interacting with polycations", Polymer, 2014, 55, 2464-2471. [PDF] [Link]


    100. Myers, D.E.; Yiv, S.; Qazi, S.; Ma, H.; Cely, I.; Shahidzadeh, A.; Arellano, M.; Finestone, E.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Uckun, F.,"CD19-antigen Q1 specific nanoscale liposomal formulation of a SYK Q2 P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells",  Integrative Biology, 2014, 6, 766-780. (1DP2OD007246-01) [PDF] [Link]


    99. Mahsan, K.; Chaudhury, I.; Cheng, J.; Safari, M.; Sadeghi, R.; Habibi-Rezaei, M.; Kokini, J.; "Immobilization of endo-inulinase on non-porous aminofunctionalized silica nanoparticles", Journal of Molecular Catalysis B: Enzymatic, 2014, 104, 48-55. [PDF] [Link]


    98. Deng, X.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J. "Trigger-responsive, fast-degradable poly(-amino ester)s for enhanced DNA unpackaging and reduced toxicity", Biomaterials, 2014, 35, 5006-5015. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS574051) [PDF] [Link]


    97. Song, Z.; Zheng, N.; Ba, X.; Yin, L.; Zhang, R.; Ma, L.; Cheng, J. "Polypeptides with Quaternary Phosphonium Side Chains: Synthesis, Characterization, and Cell-Penetrating Properties", Biomacromolecules, 2014, 15, 1491-1497. (NSF-CHE 1153122, 1DP2OD007246-01; PMC399387) [PDF] [Link]


    96. Zhang, Y.; Wang, R.; Hua, Y.; Baumgartner, R.; Cheng, J. "Trigger-Responsive Poly(β-amino ester) Hydrogels", ACS Macro Letters, 2014, 3, 693-697. (Dow Chemical Company) [PDF] [Link]


    95. Tong, R.; Tang, L.; Ma, L.; Tu, C.; Baumgartner, R.; Cheng, J. "Smart Chemistry in Polymeric Nanomedicines", Chemical Society Reviews, 2014, 43, 6982-7012. [PDF] [Link]


    94. Zhang, R.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J.; "The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides", Biomaterials, 2014, 35, 3443-3454. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS553359) [PDF] [Link]


    93. Uppada, S.B.; Erickson, T.; Wojdyla, L.; Moravec, D.N.; Song, Z.; Cheng, J.; Puri, N. "Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy", International Journal of Nanomedicine, 2014, 9, 43-53. (PMC3879016). [PDF] [Link]


    92. Lu, H.; Wang, J.; Song, Z.; Yin, L.; Zhang, Y.; Tang, H.; Tu, C.; Lin, Y.; Cheng, J. "Recent Advances in Amino Acid N-Carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-Assembly and Biological Applications", Chemical Communications, 2014, 50, 139-155. [PDF] [Link]


    91. Yin, Q.; Tong, R.; Yin, L.; Fan, T.M.; Cheng, J. "Anticancer Camptothecin-N-Poly(lactic acid) Nanoconjugates with Facile Hydrolysable Linker", Polymer Chemistry, 2014, 5, 1581-1585. (DMR 07-48834,  NSF-DMR 1309525, 1DP2OD007246-01, 1R21CA152627; NIHMS535764) [PDF] [Link].


    90. Zheng, N.; Yin, L.; Song, Z.; Ma, L.; Tang, H.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting", Biomaterials, 2014, 35, 1302-1314. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE-0809420; NIHMS535394) [PDF] [Link]




    89. Zhang, Y.; Yin, Q.; Yin, L.; Ma, L.; Tang, L.; Cheng, J. "Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability", Angew. Chem. Int. Ed., 2013, 52, 6435-6439. (Dow Chemical Company; PMC3800742, NIHMS502266) [PDF] [Link]


    88. Yin, L.; Song, Z.; Qu, Q.; Kim, K.H.; Zheng, N.; Yao, C.; Chaudhury, I.; Tang, H.; Gabrielson, N.P.; Uckun, F.M.; Cheng, J. "Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation", Angew. Chem. Int. Ed., 2013, 52, 5757-5761. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; PMC3800743, NIHMS502261) [PDF] [Link]


    87. Yin, L.; Tang, H.; Kim, K.H.; Zheng, N.; Song, Z.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Light-Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery", Angew. Chem. Int. Ed., 2013, 52, 9182-9186. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; PMC4232450, NIHMS520820) [PDF] [Link]


    86. Yin, Q.; Yap, F.Y.; Yin, L.; Ma, L.; Zhou, Q.; Dobrucki, L.W.; Fan, T.M.; Gaba, R.C.; Cheng, J. "Poly(iohexol) Nanoparticles As Constrast Agents for In Vivo X-ray Computed Tomography Imaging", J. Am. Chem. Soc., 2013, 135, 13620-13623. (1DP2OD007246-01, 1R21CA152627; PMC4232444, NIHMS522439) [PDF] [Link]


    85. Wang, J.; Xia, H.; Zhang, Y.; Lu, H.; Kamat, R.; Dobrynin, A.V.; Cheng, J.; Lin, Y. "Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures", J. Am. Chem. Soc., 2013, 135, 11417-11420. (1R21EB013379-01, NSF-CHE 1153122) [PDF] [Link] [Cover]


    84. Tang, H.; Yin, L.; Kim, K.H.; Cheng, J. "Helical Poly(arginine) Mimics with Superior Cell-Penetrating and Molecular Transporting Properties", Chemical Science, 2013, 4, 3839-3844. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; PMC4232443, NIHMS516191) [PDF] [Link]


    83. Yin, L.; Song, Z.; Kim, K.H.; Zheng, N.; Gabrielson, N.P.; Cheng, J. "Non-Viral Gene Delivery via Membrane-Penetrating, Mannose-Targeting Supramolecular Self-Assembled Nanocomplexes", Advanced Materials, 2013, 25, 3063-3070. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; PMC3757134, NIHMS499301) [PDF] [Link] [Cover]


    82. Xing, H.; Tang, L.; Yang, X.; Hwang, K.; Wang, W.; Yin, Q.; Wong, N.Y.; Dobrucki, L.W.; Yasui, N.; Katzenellenbogen, J.A.; Helferich, W.G.; Cheng, J.; Lu, Y. "Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo", Journal of Materials Chemistry B, 2013, 1, 5288-5297. (1DP2OD007246-01, 1R21CA152627; PMC3800741, NIHMS514388) [PDF] [Link


    81. Tang, L.; Cheng, J. "Nonporous Silica Nanoparticles for Nanomedicine Application", Nano Today, 2013, 8, 290-312. (1DP2OD007246-01, 1R21CA152627; PMC3757135, NIHMS481146) [PDF] [Link]


    80. Yen, J.; Zhang, Y.; Gabrielson, N.P.; Yin, L.; Guan, L.; Chaudhury, I.; Lu, L.; Wang, F.; Cheng, J. "Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cell",  Biomaterials Science, 2013, 1, 719-727. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE 1153122;  PMC3757133, NIHMS464545) [PDF] [Link]

    79. Song, Z.; Zhang, R.; Lu, H.; Gabrielson, NP; Yin, L.; Ponnusamy, E.; Cheng, J. "Synthesis and Biomedical Applications of Polyamino Acids", Materials Matters, 2013, 8, 78-84. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01) [PDF]


    78. Wang, H.; Tang, L.; Tu, C.; Song, Z.; Yin, Q.; Yin, L.; Zhang, Z.; Cheng, J. "Redox-Responsive, Core-Cross-Linked Micelles Capable of On-Demand, Concurrent Drug Release and Structure Disassembly", Biomacromolecules, 2013, 14, 3706-3712. (1DP2OD007246-01, NSF-DMR 1309525; PMC4232441, NIHMS523142) [PDF] [Link]


    77. Yin, Q.; Tong, R.; Xu, Y.; Baek, K.; Dobrucki, L.W.; Fan, T.M.; Cheng, J. "Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug-Poly(O-Carboxyanhydride) Nanoconjugates", Biomacromolecules, 2013, 14, 920-929. (DMR 07-48834, 1DP2OD007246-01, 1R21CA152627; PMC3671392, NIHMS450799) [PDF] [Link]


    76. Cameron J.A.; Milner D.J.; Lee J.S.; Cheng J;  Fang, N.X.; Jasiuk, I.M. "Employing the biology of successful fracture repair to heal critical size bone defects", Current Topics in Microbiology and Immunology, 2013, 367, 113-132. [PDF] [Link]


    75. Uckun, F.M.; Qazi, S.; Cely, I.; Sahin, K.; Shahidzadeh, A.; Ozercan, I.; Yin, Q.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Yiv, S. "Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia",  Blood, 2013, 121, 4348-4354. (1DP2OD007246-01; PMC3663427) [PDF] [Link]


    74. Zhang, Y.; Yin, Q.; Lu, H.; Xia, H.; Lin, Y.; Cheng, J. "PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation", ACS Macro Letters, 2013, 2, 809-813.(NSF-CHE 1153122, 1DP2OD007246-01; PMC3804265, NIHMS518036) [PDF] [Link] 


    73. Zhang, R.; Lu, H.; Gabrielson, N.P.; Yin, L.; Cheng, J. "Cationic α-Helical Polypeptide Template for Nonviral Gene Delivery", SurFACTS in Biomaterials, 2013, 18, 2. (1DP2OD007246-01, 1R21EB013379-01) [PDF]


    72. Mirshafiee, V.; Mahmoudi, M.; Lou, K.; Cheng, J.; Kraft, M.L. "Protein Corona Significantly Reduces Active Targeting Yield", Chemical Communications, 2013, 49, 2557-2559. (1R21CA152627; PMC3671387, NIHMS447802) [PDF] [Link]


    71. Tang L., Gabrielson N.P., Uckun F.M., Fan T.M., Cheng J. "Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates", Molecular Pharmaceuticals, 2013, 10, 883-892. (1DP2OD007246-01, 1R21CA152627; PMC3697826, NIHMS445569) [PDF] [Link]


    70. Tong, R.; Tang, L.; Gabrielson, N.P.; Yin, Q.; Cheng,J. "Polymer-Drug Nanoconjugates", book chapter in Nanoparticulate Drug Delivery Systems: Strategies, Technologies, and Applications", Ed. Y. Yeo, Wiley, April 2013. [Link]


    69. Yin, L.; Song, Z.; Kim, H.K.; Zheng, N.; Tang, H.; Lu, H.; Gabrielson, N.P.; Cheng, J. "Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery", Biomaterials, 2013, 34, 2340-2349. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01) [PDF] [Link]


    68.  Zhang, Z.; Yin, L.; Tu, C.; Song, Z.; Zhang, Y.; Xu, Y.; Tong, R.; Zhou, Q.; Ren, J.; Cheng, J. "Redox-Responsive, Core Cross-Linked Polyester Micelles", ACS Macro Lett., 2013, 2, 40-44. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE 1153122, DMR 07-48834; PMC3606897, NIHMS431405) [PDF] [Link]


    67. Zhang, Y.; Ma, L.; Deng, X.; Cheng, J. "Trigger-Responsive Chain-Shattering Polymers", Polymer Chemistry, 2013, 4, 224-228. (Dow Chemical Company) [PDF] [Link]




    66. Tang, L.; Yang, X.; Dobrucki, L.W.; Chaudhury, I.; Yin, Q.; Yao, C.; Lezmi, S.; Helferich, W.G.; Fan, T.M.; Cheng, J.  "Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugate for targeted dual-modal imaging of lymph nodes with metastatic tumors", Angew. Chem. Int. Ed., 2012, 51, 12721-12726. (1DP2OD007246-01, 1R21CA152627; NIHMS512609) [PDF] [Link] 


    65. Gabrielson, N.P.; Lu, H.; Yin, L.; Li, D.; Wang, F.; Cheng, J. "Reactive and Bioactive Cationic a-Helical Polypeptide Template for Non-Viral Gene Delivery", Angew. Chem. Int. Ed., 2012, 51, 1143-1147. (NSF-CHE-0809420, 1R21EB009486-01, 1DP2OD007246-01, 1R21CA152627; PMC3555134, NIHMS400098) [PDF] [Link]


    64. Tong, R.; Cheng, J. "Zinc complex mediated regioselective O-acylation of therapeutic agents", Chemical Science, 2012, 3, 2234-2239. [PDF] [Link]


    63. Tong, R.; Gabrielson, N.P.; Fan, T.M.; Cheng, J. "Polymeric Nanomedicine Based on Poly(lactide) and Poly(lactic-co-glycolide)", Current Opinion in Solid State & Materials Science, 2012, 16, 323-332. (PMC3728009, NIHMS439167) [PDF] [Link] 


    62. Tong, R.; Tang, L.; Cheng, J., "Development and Application of Anticancer Nanomedicine", Nanostructure Science and Technology in "Multifunctional Nanoparticles for Drug Delivery Applications: Imaging, Targeting and Delivery", Ed. by Svenson, S and Prudhomme, RK., 2012, 31-46. [PDF] [Link]


    61. Cely, I.; Yiv, S.;Yin, Q.; Shahidzadeh, A.; Tang, L.; Cheng, J.; Uckun, F.M. "Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles", J. Anal. Oncol., 2012, 1, 1-9. (1DP2OD007246-01; PMC3668349, NIHMS406536) [PDF] [Link]


    60. Li, L.; Yin, Q.; Cheng, J., Lu, Y. "Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells", Advanced Healthcare Materials, 2012, 1, 567-572. (1DP2OD007246-01, 1R21CA152627) [PDF] [Link]


    59. Gabrielson, N. P.; Lu, H.; Yin, L.; Kim, K.H.; Cheng, J. "A Cell-Penetrating Helical Polymer for siRNA Delivery to Mammalian Cells", Molecular Therapy, 2012, 20, 1599-1609. (NSF-CHE-0809420, 1R21EB013379-01, 1DP2OD007246-01; PMC3412491) [PDF] [Link]


    58. Tang, L.; Azzi, J.;  Kwon, M.; Mounayar, M.; Tong, R.; Yin, Q.; Moore, R.; Skartsis, N.; Fan, T.M.;  Abdi, R.; Cheng, J. "Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A",  Journal of Transplantation, 2012, 2012, 896141. (1DP2OD007246-01, 1R21CA152627; PMC3321582) [PDF] [Link]


    57. Tang, H.; Yin, L.; Lu, H.; Cheng, J. "Water-Soluble Poly(L-serine)s with Elongated and Charged Side-Chains: Synthesis, Conformations and Cell-Penetrating Properties", Biomacromolecules, 2012, 13, 2609-2615. (1R21EB013379-01, 1DP2OD007246-01; PMC3555145, NIHMS401030) [PDF] [Link]


    56. Tang, L.; Fan, T.M.; Borst, L.B.; Cheng, J. "Synthesis and Biological Response of Size-Specific, Monodisperse Drug-Silica Nanoconjugates", ACS Nano., 2012, 6, 3954-3966. (1DP2OD007246-01, 1R21CA152627; PMC3555148, NIHMS372943) [PDF] [Link]


    55.  Lu, Y.; Yin, L.; Zhang, Y.; Zhang, Z.; Xu, Y.; Tong, R.; Cheng, J. "Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-L-serine Carboxyanhydrides", ACS Macro Letters, 2012, 1, 441-444. (DMR 07-48834,  1DP2OD007246-01, 1R21EB013379-01; PMC3555137, NIHMS363858) [PDF] [Link]


    54. Tong, R.; Cheng, J. "Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates", Macromolecules, 2012, 45, 2225-2232. (DMR 07-48834, 1DP2OD007246-01; PMC3555138, NIHMS359696) [PDF] [Link]


    53. Zhang, Z.; Yin, L.; Xu, Y.; Ren, J.; Cheng, J. "Facile Functionalization of Polyesters through Thiol-yne Chemistry for the Design of Degradable, Cell‒Penetrating and Gene Delivery Dual‒Functional Agents",  Biomacromolecules, 2012, 13, 3456-3462. (1R21EB013379-01, 1DP2OD007246-01, NSF-CHE 1153122; PMC3606898, NIHMS417829) [PDF] [Link] 


    52. Chen, K.; Tang, L.; Garcia, M.A.; Wang, H.; Lu, H.; Lin,  W.; Hou, S.; Yin, Q.; Shen, C.K.F.; Cheng, J.; Tseng, H.R. "The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles", Biomaterials, 2012, 33, 1162-1169. (1R21CA152627; PMC3786683, NIHMS333953) [PDF] [Link]




    51. Lu, H.; Wang, J.; Bai, Y.; Lang, J.W.; Liu, S.; Lin, Y.; Cheng, J. "Ionic Polypeptides with Unusual Helical Stability", Nature Communications, 2011, 2, 206. (NSF-CHE-0809420, DMR 07-48834, 1R21EB009486-01, 1DP2OD007246-01, 1R21CA139329) [PDF] [Link]


    50. Mishra, A.;  Lai, G.H.; Schmidt, N.W.; Sun, V.Z.; Rodriguez, A.R., Tong, R.; Tang, L.; Cheng, J.; Deming, T.J.;  Kamei, D.T.; Wong, G.C.L. "Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions", PNAS, 2011, 108, 16883-16888. (PMC3193208) [PDF] [Link]


    49. Wang, J.; Lu, H.; Kamat, R.; Pingali, S.V.; Urban, V.S.; Cheng, J.; Lin, Y. "Supramolecular Polymerization from Polypeptide-Grafted Comb Polymers", J. Am. Chem. Soc., 2011, 133, 12906-12909. (NSF-CHE-0809420) [PDF] [Link] 


    48. Bai, Y.; Lu, H.; Ponnusamy, E.; Cheng, J. "Synthesis of Hybrid Block Copolymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of NCA", Chemical Communications, 2011, 47, 10830-10832. (NSF-CHE-0809420, 1R21EB009486-01, 1DP2OD007246-01) [PDF] [Link]


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    46. Lu, H.; Bai, Y.; Wang, J.; Gabrielson, N.; Wang, F.; Lin, Y.; Cheng, J. "Ring-Opening Polymerization of g-(4-Vinylbenzyl)-L-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides", Macromolecules, 2011, 44, 6237-6240. (NSF-CHE-0809420, 1R21EB009486-01, 1DP2OD007246-01; PMC3222942, NIHMS312521) [PDF] [Link] [Cover]


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    43. Tong, R., Tang, L., Yin, Q., Cheng, J. "Drug-polyester conjugated nanoparticles for cancer drug delivery", IEEE. Eng. Med. Biol. Soc., 2011, 3, 8337-8339. (DMR 07-48834) [PDF] [Link] 


    42. Li, D.; Zhou, J.; Chowdhury, F.; Cheng, J.; Wang, N.; Wang, F. "Role of mechanical factors in fate decisions of stem cells." Regenerative Medicine, 2011, 6, 229-240. (PMC3128460, NIHMS303388) [PDF] [Link]




    41. Chan, J.M.; Zhang, L. F.; Tong, R.; Ghosh, D.; Gao, W.; Liao, G.; Yuet, K.; Gray, D.; Rhee, J.W.; Cheng, J.; Golomb, G.; Libby, P; Langer, R.; Farokhzad, O. "Spatiotemporal Controlled Delivery of Nanoparticles to Injured Vasculature", PNAS, 2010, 107, 2213-2218. (PMC2836709) [PDF] [SI] [Link]


    40. Li, C.; Zhang, Y.; Hu, J..; Cheng, J.; Liu, S. "Reversible Three-State Switching of Multicolor Fluorescence Emission via Multiple Stimuli-Modulated FRET Processes within Thermoresponsive Polymeric Micelles", Angew. Chem. Int. Ed., 2010, 49, 5120-5124. [PDF] [SI] [Link]


    39. Azzi J, Tang L, Moore R, Tong R, El Haddad N, Akiyoshi T, Mfarrej B, Yang S, Jurewicz M, Ichimura T, Lindeman N, Cheng J, Abdi R. "Polylactide-Cyclosporin A Nanoparticles for Targeted Immunosuppression", FASEB J., 2010, 24, 3927-3938. (DMR 07-48834,  1R21CA139329-01, 1R21EB009486-01; PMC2996919) [PDF] [Link]


    38. Yang, X.; Shi, C.; Tong, R.; Qian, W.; Zhau, H. E.; Wang, R.; Zhu, G., Cheng, J. Yang, Y.; Cheng, T.; Henary, M.; Strekowski, L.; Chung, L.W.K. "Near Infrared Heptamethine Cyanine Dyes: 1. Cancer Imaging",  Clinical Cancer Research, 2010, 16, 2833-2844. (PMC2871283, NIHMS188889) [PDF] [Link]


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    35. Chaney, E.J.; Tang, L.; Tong, R.; Cheng, J.; Boppart, S.A. "Lymphatic Biodistribution of Polylactide Nanoparticles", Molecular Imaging, 2010, 9, 153-162. (DMR 07-48834,  R21CA139329-01; PMC3699327, NIHMS466991) [PDF] [Link]


    34. Tong, R.; Cheng, J. "Controlled Synthesis of Camptothecin-Polylactide Conjugates", Bioconjugate Chem., 2010, 21, 111-121. (DMR 07-48834,  1R21CA139329-01; PMC2809133, NIHMS164604) [PDF] [Link]


    33. Tong, R.; Yala, L.; Fan, T.M.; Cheng, J. "The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells", Biomaterials, 2010, 31, 3043-3053 (1R21CA139329, 1R21EB009486-01, DMR 07-48834; PMC3222157, NIHMS171453) [PDF] [Link]




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    31. Cao, Z.; Tong, R.; Xu, W.; Wong, G.W.L.; Cheng, J.; Lu, Y. "Reversible cell-specific delivery of chemotherapy drugs using aptamer-functionalized liposomes", Angew. Chem. Int. Ed., 2009, 48, 6494-6498. (DMR 07-48834) [PDF] [SI] [Link]


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    29. Tong, R.; Christian, D.A.; Tang, L.; Cabral, H.; Baker, J.R. Jr.; Kataoka, K.; Discher, D.; Cheng, J. "Nanopolymeric Therapeutics", MRS Bulletin, 2009, 34, 422-431. (DMR 07-48834) [PDF] [Link]


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    26. Lu, H.; Cheng, J. "Controlled Ring-Opening Polymerization of Amino Acid N-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides", J. Am. Chem. Soc., 2008, 130, 12562-12563. (NSF-CHE-0809420) [PDF] [SI] [Link]


    25. Tong, R.; Cheng, J. "Paclitaxel-Initiated, Controlled Polymerization of Lactide for the Formulation of  Polymeric Nanoparticulate Delivery Vehicles", Angew. Chem. Int. Ed., 2008, 47, 4830-4834. (DMR 07-48834) [PDF] [SI] [Link]


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    22. Lu, H.; Cheng, J. "Hexamethyldisilazane-Mediated Controlled Polymerization of α-Amino Acid-NCarboxyanhydrides", J. Am. Chem. Soc., 2007, 129, 14114-14115.[PDF] [SI] [Link]


    21. Tong, R.; Cheng, J. "Anticancer Polymeric Nanomedicines", Polymer Reviews, 2007, 47, 345-381. [PDF] [Link]


    20. Karp, J.M., Yeh, J.; Eng, G.; Fukuda, J.; Blumling, J.; Suh, K.Y.; Cheng, J.; Mahdavi, A.; Jeffrey Borenstein, J.; Langer, R.; Khademhosseini, A.  "Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells", Lab Chip, 2007, 7, 786 - 794. [PDF] [Link]


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    18. Farokhzad, O.C.; Cheng, J. (co-first author); Teply, B.A.; Sherifi, I.; Khademhosseini, A.; Langer, R. "In vivo prostate tumor reduction after single administration of docetaxel encapsulated nanoparticle-aptamer bioconjugates", PNAS, 2006, 103, 6315-6320.  [PDF] [Link]


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    23. Cheng, J.; Ying, H. "Cyclic dynamic polyureas for polymeric urea processing", US 62/111, 572, 2015. (TF15006)

    22. Cheng, J.; Cai, K. "Trigger Responsive Drug Conjugate for High Loading Nanoencapsulates", US 62/120,821, 2015, (TF14168)

    21. Cheng, J.; Ying, H.; Zhang, Y. "Dynamic urea bonds for polymers", US 62/069, 385, 2014. (TF14085)

    20. Cheng, J.; Ying, H. "Hydrolysable polymers with dynamic urea bonds", US 62/069, 384, 2014. (TF14085)

    19. Cheng, J.; Yen, J,. "Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells, Provision Patent Application", US 62/029,964, 2014. (TF14100)

    18. Rogers, JA; Kang, S.; Hwang, S.; Cheng, J.; Zhang, Z.; Ying, H. "Transient Electronic Devices Comprising Inorganic or Hybrid Inorganic and Organic substrates and encapsulates, US 61/811,603.

    17. Cheng, J.; Ying, H. "Dynamic urea bonds for reversible and self-healing polymers", US 61/799,144, 2013. (TF 12136)

    16. Cheng, J.; Yin, L. "Supramolecular Self-Assembled Nanoparticles Mediate Oral Delivery of Therapeutic TNF-a siRNA Against Systemic Inflammation" US 61/810,983, 2013. (TF13054)

    15. Cheng, J.; Zhang, Y. "Trigger-Responsive, Degradable Polymers" US 61/649,205, US 61/648,715, 2012. (TF11176)

    14. Cheng, J.; Lu, H. "Ionic Polypeptides with Unusual Helical Stability" Converted US 61/418,269, WO PCT/US2011/062656, 2011. (TF10060)

    13. Cheng, J.; Gabrielson. "Supramolecular Assembly for Non-Viral Gene Delivery" US 61/371,618 2010, WO PCT/US2011/046791, 2011. (TF10042).

    12. Cheng, J.; Tang, L. "Preparation of Degradable Silica-Drug Conjugated Nanoparticle with Monodisperse Particle Sizes" US 61/418,230 2010, WO PCT/US2011/062548, 2011. (TF09149).

    11.  Cheng, J.; Tong, R. "Particulate Drug Delivery" PRO 60/892,834, 2007; US 12/041,529 2008; WO PCT/US2008/055590, 2008. (TF06188)

    10. Chung, L.W.K.; Yang, X.; Cheng, J.; Tong, R. "Small molecule mediated cancer targeting and therapy" provisional application, 2008.

    9. Cheng, J.; Lu, H." Controlled Ring-Opening Polymerization of NCA Using Organosilicon Reagents", provisional application, 2008.


    8. Cheng, J; Tong, R. "Particulate Drug Delivery", PCT International Application, 2008.


    7. Farokhzad, O.; Cheng, J.; Teply, B.; Langer, R.S. "System for targeted delivery of therapeutics agents", PCT international application, 2007, licensed by Bind Bioscience, Inc.


    6. Jon, S.; Farokhzad, O.C.; Langer, R.S.; Cheng, J.  "Coated Controlled Release Polymer Particles as Efficient Oral Delivery Vehicles for Biopharmaceuticals", PCT. International Application, 2006, licensed by Bind Bioscience, Inc.


    5. Bellocq, N.C.; Cheng, J; Pun, S.H.; Davis, M.E.  "Carbohydrate-Modified Polymers, Compositions and Uses Related Thereto", PCT. International Application, 2004, licensed by Insert Therapeutics, Inc.


    4. Cheng, J; Davis, M.E.; Khin, K.T. "Cyclodextrin-Based Polymers for Therapeutics Delivery", PCT. International Application, 7,270,808, issued in 2007, licensed by Insert Therapeutics, Inc.


    3. Pun, S.H.; Gonzalez, H.; Davis, M.E.; Bellocq, N.C.; Cheng, J. "Complexing agents for compositions containing inclusion complexes", US 716, 6302, issued in 2007, licensed by Insert Therapeutics, Inc.


    2. Pun, S.H.; Gonzalez, H.; Davis, M.E.; Bellocq, N.C.; Cheng, J. "Compositions containing inclusion complexes", PCT. International Application, 701,8609, issued, licensed by Insert Therapeutics, Inc.  


    1. Deming. T.J.; Cheng, J., "Transition Metal Initiators for Controlled Poly(β-peptide) Synthesis from Beta-Lactam Monomers ", 681,8732, issued in 2004. Licensed.