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Publications
80. Wang, J.; Xia, H.; Zhang, Y.; Lu, H.; Kamat, R.; Dobrynin, A.; Cheng, J.; Lin, Y. "Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures", Journal of the American Chemical Society, accepted.
79. Tang, L.; Cheng, J. "Nonporous Silica Nanoparticles for Nanomedicine Application", Nano Today, accepted.
78. Yen, J.; Zhang, Y.; Gabrielson, N.P.; Yin, L.; Guan, L.; Chaudhury, I.; Lu, L.; Wang, F.; Cheng, J. "Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cell", Biomaterials Science, accepted.
77. Zhang, Y.; Yin, Q.; Yin, L.; Ma, L.; Tang, L.; Cheng, J. "Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability", Angew. Chem. Int. Ed. accepted.
76. Yin, L.; Song, Z.; Qu, Q.; Kim, KH; Zheng, N.; Yao, C.; Chaudhury, I.; Tang, H.; Gabrielson, NP; Uckun, FM; Cheng, J. "Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation ", Angew. Chem. Int. Ed. accepted.
75. Yin, Q.; Tong, R.; Xu, Y.; Dobrucki, LW; Fan, TM; Cheng, J. "Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug-Poly(O-Carboxyanhydride) Nanoconjugates" Biomacromolecules, accepted.
74. Cameron JA; Milner DJ; lee JS; Cheng J; NX Fang; Jasiuk IM. "Employing the biology of successful fracture repair to heal critical size bone defects" Current Topics in Microbiolog and Immunology, accepted.[PDF] [Link]
73. Uckun. F.M.; Qazi, S.; Cely, I.; Sahin, K.; Shahidzadeh, A.; Tuzcu, M.; Ilhan, N.; Ozercan, I.; Song, Z.; Rodriguez. A.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Yiv, S., Blood, accepted.
72. Yin, L.; Song, Z.; Kim, KH; Zheng, N.; Gabrielson, NP; Cheng, J. "Non-Viral Gene Delivery Based on Supramolecular Self-Assembled Nanocomplexes via Membrane Penetration and Mannose Targeting", Advanced Materials, accepted.
71. Zhang, R.; Lu, H.; Gabrielson, N.; Yin, L.; Cheng, J. "Cationic α-Helical Polypeptide Template for Nonviral GeneDelivery", SurFACTS in Biomaterials, 2013,18,2. [PDF]
70. Mirshafiee, V.; Mahmoudi, M.; Lou, K.; Cheng, J.; Kraft, ML." Protein Corona Significantly Reduces Active-Targeting Yield", Chemical Communications, 2013, 49, 2557-2559.
69. Tang L, Gabrielson NP, Uckun FM, Fan TM, Cheng J. "Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates", Molecular Pharmaceuticals. 2013, 10, 883-892.
68. Tong, R.; Tang, L.; Gabrielson, N.P.; Yin, Q.; Cheng,J. "Polymer-Drug Nanoconjugates", book chapter in Nanoparticulate Drug Delivery Systems: Strategies, Technologies, and Applications", Ed. Y. Yeo, Wiley, April 2013.
67. Yin, L.; Song, Z.; Kim, K.; Zheng, N.; Tang, H.; Lu, H.; Gabrielson, N.; Cheng, J. " Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery", Biomaterials, 2013, 34, 2340-2349. [PDF] [Link]
66. Zhang, Z.; Yin, L.; Zhang, Y.; Xu, Y.; Tong, R.; Zhou, Q.; Ren, J.; Cheng, J. "Redox-Responsive, Core Cross-Linked Polyester Micelles", ACS Macro Lett., 2013, 2, 40-44. [PDF] [Link]
65. Zhang, Y.; Ma, L.; Deng, X.; Cheng, J. "Trigger-Responsive Chain-Shattering Polymers", Polymer Chemistry, 2013, 4, 224-228. [PDF] [Link]
64.Tong, R.; Gabrielson, N. P; Fan, TM.; Cheng, J. "Polymeric Nanomedicine Based on Poly(lactic acid) and Poly(lactic-co-glycolic acid)", Current Opinion in Solid State & Materials Science, 2012, 16, 323-332. [PDF] [Link]
63. Zhang, Z.; Yin, L.; Xu, Y.; Ren, J.; Cheng, J. "Facile Functionalization of Polyesters through Thiol-yne Chemistry for the Design of Degradable, Cell‒Penetrating and Gene Delivery Dual‒Functional Agents", Biomacromolecules, 2012, 13, 3456-62. [PDF] [Link]
62. Tang, H.; Yin, L.; Lu, H.; Cheng, J. "Water-Soluble Poly(L-serine)s with Elongated and Charged Side-Chains: Synthesis, Conformations and Cell-Penetrating Properties", Biomacromolecules, 2012, 13, 2609. [PDF] [Link]
61. Tang, L.; Yang, X.; Dobrucki, LW; Chaudhury, I.; Yin, Q.; Yao, C.; Lezmi, S.; Helferich, WG* Fan, TM;* Cheng, J.* "Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugate for targeted dual-modal imaging of lymph nodes with metastatic tumors", Angew Chem. Int. Ed., 2012, 124, 12893 -12898. [PDF] [Link]
60. Tong, R.; Tang, L.; Cheng, J., "Development
and Application of Anticancer Nanomedicine",
59. Cely, I.; Yiv, S.;Yin, Q.; Shahidzadeh, A.; Tang, L.; Cheng, J.; Uckun, F.M. "Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles", J. Anal. Oncology, 2012, 1: 1-8, 2012. [Link]
58. Li, L.; Yin, Q.; Cheng, J.,* Lu, Y.* "Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells", Advanced Healthcare Materials, 2012, 1, 567-572. [PDF] [Link]
57. Gabrielson, N. P.; Lu, H.; Kim, KH, Cheng, J.* "A Cell-Penetrating Helical Polymer for siRNA Delivery to Mammalian Cells", Molecular Therapy, 2012, 20, 1599-1609. [PDF] [Link]
56. Tang, L.; Azzi, A.; Kwon, M.; Mounayar, M.; Tong, R.; Yin, Q.; Moore, R.; Skartsis, R.; Fan, T. M. Abdi, R.; Cheng, J.* "Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A", Journal of Transplantation, 2012, 2012: 896141. doi:10.1155/2012/896141. [PDF] [Link]
55. Tong, R.; Cheng, J.;* "Zinc complex mediated regioselective O-acylation of therapeutic agents", Chemical Science, 2012, 3, 2234-2239. [PDF] [Link]
54. Tang, L.; Fan, TM.; Borst, LB; Cheng, J.* "Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates", ACS Nano., 2012, 6, 3954-3966 [PDF] [Link]
53 Lu, Y.; Yin, L.; Zhang, Y.; Xu, Y.; Cheng, J.* "Synthesis of water-soluble poly(α-hydroxy acids) from living ring-opening polymerization of O-benzyl-L-serine carboxy-anhydrides", ACS Macro Letters, 2012, 1, 441-444. [PDF] [Link]
52. Tong, R.; Cheng, J.* "Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates", Macromolecules, 2012, 45, 2225-2232. [PDF] [Link]
51. Gabrielson, N.; Lu, H.; Yin, L.; Li, D.; Wang, F.; Cheng, J.;* "Reactive and Bioactive Cationic g-Helical Polypeptide Template for Non-Viral Gene Delivery", Angewandte Chemie International Edition, 2012, 51, 1143-1147 [PDF] [Link]
50. Chen, K.; Tang, L.; Garcia, MA; Wang, H.; Lu, H.; Lin,, WY; Hou, S.; Yin., Q.; Shen, CKF.; Cheng, J.;* Tseng, HR.* "The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles", Biomaterials, 2012, 33, 1162-1169. [PDF] [Link]
49. Wang, J.; Lu, H.; Ren, Y.; Zhang, Y.; Morton, M.; Cheng, J.*; Lin, Y.* "Interrupted Helical Structure of Grafted Polypeptides in Brush-Like Macromolecules", Macromolecules, 2011, 44, 8699-8708. [PDF] [Link]
48. Mishra, A.; Lai, GH; Schmidt, NW; Sun, VZ; Rodriguez, AR, Tong, R.; Tang, L.; Cheng, J.; Deming, TJ; Kamei, DT; Wong, GCL. "Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions", Proceedings of the National Academy of Sciences, 2011, 108, 16883-16888. [PDF]
47. Bai, Y.; Lu, H.; Ponnusamy, E.; Cheng, J.* "Synthesis of Hybrid Block Copolymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of NCA", Chem. Commun. 2011, 47, 10830-10832. [PDF]
46. Zhang, Y.; Lu, H.; Yao, L.; Cheng, J.* "Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultra-Stable Helical Conformations", Macromolecules, 2011, 44, 6641-6644. [PDF]
45. Lu, H.; Bai, Y.; Wang, J.; Gabrielson, N.; Wang, F.; Lin, Y.; Cheng, J.* "Ring-Opening Polymerization of g-(4-Vinylbenzyl)-L-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides", Macromolecules, 2011, 44, 6237. [PDF] Cover image of Macromolecules issue of Aug. 23, 2011.
44. Cheng, J.; Deming, TJ, "Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides." Top Curr. Chem. 2011, DOI: 10.1007/128_2011_173 [PDF]
43. Wang, J.; Lu, H.; Kamat, R.; Pingali, S. V.; Urban, V. S.; Cheng, J.*; Lin, Y.* "Supramolecular Polymerization from Polypeptide-Grafted Comb Polymers", Journal of American Chemical Society, 2011, 133, 12906-12909. [PDF]
42. Lu, H.; Wang, J.; Bai, Y.; Lang, J. Liu, S. Lin, Y.; Cheng, J.* "Ionic Polypeptides with Unusual Helical Stability", Nature Communications, 2011, 2, 206. [PDF]
41. Li, D.; Zhou, J.; Chowdhury, F.; Cheng, J.; Wang, N.; Wang, F. "The role of mechanical factors in fate decisions of stem cells." Regenerative Medicine, 2011, 6, 229-240. [PDF]
40. Gabrielson, N.; Xu, Y.; Cheng, J.;* "Oligoarginine-Containing Lipoplex for Non-Viral Gene Delivery", Biomaterials, 2010, 31, 9117-9127. [PDF]
39. Li, C.; Zhang, Y.; Hu, J..; Cheng, J.*; Liu, S.* "Reversible Three-State Switching of Multicolor Fluorescence Emission via Multiple Stimuli-Modulated FRET Processes within Thermoresponsive Polymeric Micelles", Angewandte Chemie International Edition, 2010, 49, 5120-5124. [PDF].
38. Azzi J, Tang L, Moore R, Tong R, El Haddad N, Akiyoshi T, Mfarrej B, Yang S, Jurewicz M, Ichimura T, Lindeman N, Cheng J, Abdi R. "Polylactide-Cyclosporin A Nanoparticles for Targeted Immunosuppression", FASEB J., 2010, 24, 3927-3938. [PDF].
37. Yang, X.; Shi, C.; Tong, R.; Qian, W.; Zhau, H. E.; Wang, R.; Zhu, G., Cheng, J. Yang, Y.; Cheng, T.; Henary, M.; Strekowski, L.; Chung, LWK . "Near Infrared Heptamethine Cyanine Dyes: 1. Cancer Imaging", Clinical Cancer Research, 2010, 16, 2833-2844. [PDF]
36. Chan, J.; Zhang, L. F.; Tong, R.; Ghosh, D.; Gao, W.; Liao, G.; Yuet, K.; Gray, D.; Rhee, J. W.; Cheng, J.; Golomb, G.; Libby, P; Langer, R.; Farokhzad, O. "Spatiotemporal Controlled Delivery of Nanoparticles to Injured Vasculature", Proceedings of the National Academy of Sciences, 2010, 107, 2213-2218 [PDF].
35. Tong, R.; Coyle, V.J; Li, T.; Barger, A.M., Fan, TM*; Cheng, J.* "Polylactide Nanoparticles Containing Stably-Incorporated Cyanine Dyes for In Vitro and In Vivo Imaging Applications", Microscopy Research and Technique, 2010, [PDF] [Journal Cover].
34. Chaney, E. J.; Tang, L.; Tong, R.; Rezaeipoor, R.; Cheng, J.; Boppart, S. "Lymphatic Biodistribution of Cy5-LA50/PLA-mPEG5k Nanoparticles for Targeting Metastatic Cells", Molecular Imaging, 2010, 9, 153-162 [PDF].
33. Tong, R.; Cheng, J.* "Controlled Synthesis of Camptothecin-Polylactide Conjugates", Bioconjugate Chem., 2010, 21, 111-121 [PDF].
32. Tong, R.; Yala, L.; Fan, TM.; Cheng, J.* "Controlled Formulation of Paclitaxel-Polylactide Conjugate Nanoparticles", Biomaterials, 2010, 31, 3043-3053 [PDF].
31. Yigit, MV; Mishra, A.; Tong, R.; Cheng, J.; Wong, GCL.; Lu, Y. "Inorganic mercury detection and controlled release of chelating agents from ion-responsive PEG-liposomes", Chem. Biol., 2009, 16, 937-942 [PDF]
30. Tong, R., Tang, L., Yala, L., Cheng, J.* "Controlled formulation of doxorubicin-polylactide nanoconjugates for cancer drug delivery", IEEE. Eng Med Biol Soc. 2009, 1, 2400-2402.
29. Lu, H.; Wang, J.; Lin, Y.*; Cheng, J.* "One-Pot Synthesis of Brush-Like Polymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of Amino Acid N-Carboxyanhydrides", Journal of American Chemical Society, 2009, 131, 13582-13583 [PDF] Highlighted by Chemical and Engineering News.
28. Tong, R.; Christian, D.A.; Tang, L.; Cabral, H.; Baker, J.R. Jr.; Kataoka, K.; Discher, D.; Cheng, J. "Nanopolymeric Therapeutics", MRS Bulletin, 2009, 34, 422-431 [PDF]
27. Cao, Z.; Tong, R.; Xu, W.; Wong, GWL.;* Cheng, J.;*, Lu, Y.* "Reversible cell-specific delivery of chemotherapy drugs using aptamer-functionalized liposomes", Angewandte Chemie International Edition, 2009, 48, 6494-6498.[PDF]
26. Tong, R.; Cheng, J.* "Ring-Opening Polymerization Mediated-Controlled Formulation of Polylactide Nanoparticles", Journal of American Chemical Society, 2009, 131, 4744-4754 [PDF]
25. Lee, JS.; Cheng, J.; Kim, KY. "Next Generation Nanosolutions for Cancer Treatment and Diagnosis", Cancer and Chemotherapy Review, 2008, 3, 144-151.[PDF]
24. Lu, H.; Cheng, J. * "Controlled Ring-Opening Polymerization of Amino Acid N-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides", Journal of American Chemical Society, 2008, 130, 12562-12563 [PDF]
23. Tong, R.; Cheng, J.* "Paclitaxel-Initiated, Controlled Polymerization of Lactide for the Formulation of Polymeric Nanoparticulate Delivery Vehicles", Angewandte Chemie International Edition, 2008, 47, 4830-4834. [PDF].
22. Teply, BA; Tong, R.; Jeong, SY; Luther,G.; Sherifi, I.; Yim, CH; Khademhosseini, A.; Farokhzad,OC; Langer R.*; Cheng J.* "Charge-Coupled Polymeric Microparticles and Micromagnets Allow External Modulation of the Bioavailability of Orally Delivered Macromolecules", Biomaterials, 2008, 29, 1216-1223. [PDF]
21. Lu, H.; Cheng, J. * "Hexamethyldisilazane-Mediated Controlled Polymerization of α-Amino Acid-NCarboxyanhydrides", Journal of American Chemical Society, 2007, 129, 14114-14115.[PDF]
20. Tong, R.; Cheng, J. *"Anticancer Polymeric Nanomedicines", Polymer Reviews, 2007, 47, 345-381. [PDF]
19. Karp J. M., Yeh, J.;, Eng, G. , Fukuda, J.; Blumling, J.; Suh, K. Y.; Cheng, J.; Mahdavi, A.; Jeffrey Borenstein, J.; Langer, R.; Khademhosseini, A. "Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells", Lab Chip, 2007, 7, 786 - 794. [PDF]
18. Cheng, J.; Teply, B.; Sherifi, I.; Sung, J.; Luther. G.; Gu, F.X.; Levy-Nissenbaum, E.; Langer, R. Farokhzad, OC. "Formulation of Functionalized PLGA-PEG Nanoparticles for In Vivo Targeted Drug Delivery", Biomaterials, 2007, 28, 869-876. [PDF]
17. Farokhzad, OC; Cheng J. (co-first author), Teply, B.A.; Sherifi I.; Khademhosseini A.; Langer, R. "In vivo prostate tumor reduction after single administration of docetaxel encapsulated nanoparticle-aptamer bioconjugates", Proceedings of the National Academy of Sciences, 2006, 103, 6315-6320. [PDF]
16. Cheng, J. Zeidan, R. Mishra, M., Liu, A., Pun, SH., Kulkarni, RP; Jensen, GS, Bellocq, N., and Davis ME;, Structure-Function Correlation of Chloroquine and Analogues as Transgene Expression Enhancers in Non-Viral Gene Delivery. J. Med. Chem., 2006, 49, 6522-6531.[PDF]
15. Schluep T., Hwang J., Cheng J., Heidel, J.D.; Derek W., Bartlett, DW, Davis M.E. "Preclinical Efficacy of the Camptothecin-Polymer Conjugate IT-101 in Multiple Cancer Models." Clinical Cancer Research, 2006, 12, 1606-1614. [PDF]
14. Cheng, J.; Teply, B. Yim, C.; Jeong, SY, Sherifi, I.; Jon, S.; A. Khademhosseini; Farokhzad, OC; Langer, RS. "Magnetically Responsive Polymeric Microparticles for Oral Delivery of Protein Drugs", Pharmaceutical Research, 2006, 23, 557-564. [PDF]
13. Fukuda, J.; Khademhosseini A.; Yeh, J.; Eng, G.; Cheng, J., Farokhzad, OC; Langer, RS. "Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components", Biomaterials, 2006, 27,1479-86. [PDF]
12. Schluep, T.; Cheng, J.; Khin KT, Davis, ME "Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor bearing mice", Cancer Chemotherapy and Pharmacology, 2006, 57, 654-662. [PDF]
11. Cheng, J. and Pun, S. H.; "Nanotechnology in Drug Delivery", In "An Executive's Guide to Nanotechnology", Editor: Lynn Foster, Prentice Hall, 2005.
10. Farokhzad, O.; Khademhosseini, A.; Jon, S.; Hermmann, A.; Cheng, J.; Chin, C.; Kiselyuk, A.; Eng, G.; Langer, R. "Microfluidic System for Studying the Interaction of Nanoparticles and Microparticles with Cells" Analytical Chemistry, 2005, 77, 5453-5459. [PDF]
9. Pun, S. H.; Bellocq, N. C.; Cheng, J.; Grubbs, B. H.; Jensen, G. S.; Davis, M. E.; Tack, F.; Brewster, M.; Janicot, M.; Janssens, B.; Floren, W.; Bakker, A.; "Biodistribution of RNA-cleaving DNA Enzyme (DNAzyme) to Tumor Tissue by Transferrin-Modified, Cyclodextrin-Based Particles", Cancer Biology and Therapy, 2004, 3, 641-650. [PDF]
8. Cheng, J.; Khin, K. T.; Davis, M. E. "Antitumor Activity of (β-Cyclodextrin Polymer-Camptothecin Conjugates", Molecular Pharmaceutics, 2004, 1, 183-193. [PDF]
7. Cheng, J.; Khin, K. T.; Jensen, G. S.; Liu, A.; Davis, M. E. "Synthesis of Linear, β-Cyclodextrin-Based Polymers and Their Camptothecin Conjugates", Bioconjugate Chemistry, 2003, 14, 1007-1017. [PDF]
6. Cheng, J.; Deming, T. J., "Controlled Polymerization of Beta-lactams Using Metal-Amido Complexes: Synthesis of Block Copoly(β-peptides)", Journal of American Chemical Society, 2001, 123, 9457-9458. [PDF]
5. Cheng, J.; Deming, T. J. "Synthesis and Conformational Analysis of Optically Active Poly(β-peptides)", Macromolecules, 2001, 34, 5169-5174. [PDF]
4. Cheng, J.; Ziller, J. W.; Deming, T. J. "Synthesis of Optically Active β-Amino Acid N-Carboxyanhydrides". Organic Letters, 2000, 2, 1943-1946. [PDF]
3. Cheng, J.; Deming, T. J. "Screening of Optically Active Nickel Initiators for Enantioasymmetric Polymerization of α-Benzyl Glutamate-N-Carboxyanhydride". Macromolecules, 1999, 32, 4745-4747. [PDF]
2. Smith, G. V.; Cheng, J.; Song, R. "New Enantioselective Heterogeneous Catalysts", Catalysts Letters, 1997, 45, 73-78.
1. Smith, G. V.; Cheng, J.; Song, R. "Enantioselective Hydrogenation of Prochiral C=C Bonds over Nobel Metal Catalysts Supported by β-Cyclodextrin Polymer", Catalysts of Organic Reactions, 1996, 479-484.
Patents Cheng, J.; Reza A. Tong, R. "Immunosuppression using nanoparticles", provisional application, 2008. Chung, LWK; Yang, X.; Cheng, J.; Tong, R. "Small molecule mediated cancer targeting and therapy" provisional application, 2008 Cheng, J.; Lu, H." Controlled Ring-Opening Polymerization of NCA Using Organosilicon Reagents", provisional application, 2008.
Cheng, J; Tong, R. "Particulate Drug Delivery", PCT International Application, 2008. Farokhzad, O.; Cheng, J.; Teply, B.; Langer, R. S. "System for targeted delivery of therapeutics agents", PCT international application, 2007, licensed by Bind Bioscience, Inc.
Jon, S.; Farokhzad, O. C.; Langer, R. S.; Cheng, J. "Coated Controlled Release Polymer Particles as Efficient Oral Delivery Vehicles for Biopharmaceuticals", PCT. International Application, 2006, licensed by Bind Bioscience, Inc.
Bellocq, N. C.; Cheng, J; Pun, S. H.; Davis, M.E. "Carbohydrate-Modified Polymers, Compositions and Uses Related Thereto", PCT. International Application, 2004, licensed by Insert Therapeutics, Inc.
Cheng, J; Davis, M. E.; Khin, K. T. "Cyclodextrin-Based Polymers for Therapeutics Delivery", PCT. International Application, 7,270,808, issued in 2007, licensed by Insert Therapeutics, Inc.
Pun, S. H.; Gonzalez, H.; Davis, M. E.; Bellocq, N. C.; Cheng, J. "Complexing agents for compositions containing inclusion complexes", US 716, 6302, issued in 2007, licensed by Insert Therapeutics, Inc.
Pun, S. H.; Gonzalez, H.; Davis, M. E.; Bellocq, N. C.; Cheng, J. "Compositions containing inclusion complexes", PCT. International Application, 701,8609, issued, licensed by Insert Therapeutics, Inc.
Deming. T. J.; Cheng, J., "Transition Metal Initiators for Controlled Poly(β-peptide) Synthesis from Beta-Lactam Monomers ", 681,8732, issued in 2004. Licensed.
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